Chronic and Acute Pain Research

Generalised Pain

Vickers, A. J., Vertosick, E. A., Lewith, G., MacPherson, H., Foster, N. E., Sherman, K. J., . Linde, K. (2017). Acupuncture for Chronic Pain: Update of an Individual Patient Data Meta-Analysis. J Pain. doi:10.1016/j.jpain.2017.11.005

MacPherson, H., Vertosick, E. A., Foster, N. E., Lewith, G., Linde, K., Sherman, K. J., . . . Vickers, A. J. (2016). The persistence of the effects of acupuncture after a course of treatment: A meta-analysis of patients with chronic pain. Pain. doi:10.1097/j.pain.0000000000000747

MacPherson, H., Vickers, A., Bland, M., Torgerson, D., Corbett, M., Spackman, E., . . . Watt, I. (2017). Programme Grants for Applied Research Acupuncture for chronic pain and depression in primary care: a programme of research. Southampton (UK): NIHR Journals Library

MacPherson, H., Vertosick, E., Lewith, G., Linde, K., Sherman, K. J., Witt, C. M., & Vickers, A. J. (2014). Influence of control group on effect size in trials of acupuncture for chronic pain: a secondary analysis of an individual patient data meta-analysis. PLoS One, 9(4), e93739. doi:10.1371/journal.pone.0093739

Chiu, H. Y., Hsieh, Y. J., & Tsai, P. S. (2017). Systematic review and meta-analysis of acupuncture to reduce cancer-related pain. Eur J Cancer Care (Engl), 26(2). doi:10.1111/ecc.12457

Schug, S. A., Palmer, G. M., Scott, D. A., Halliwell, R., & Trinca, J. (2016). Acute pain management: scientific evidence, fourth edition, 2015. Med J Aust, 204(8), 315-317.

Scottish Incollegiate Guidelines Network (SIGN). Management of Chronic Pain (SIGN publication no. 136). Scottish Incollegiate Guidelines Network (SIGN); 2013.


Lower Back Pain

Qaseem, A., Wilt, T. J., McLean, R. M., & Forciea, M. A. (2017). Noninvasive Treatments for Acute, Subacute, and Chronic Low Back Pain: A Clinical Practice Guideline From the American College of Physicians. Ann Intern Med, 166(7), 514-530. doi:10.7326/m16-2367

Chou R, Deyo R, Friedly J, Skelly A, Hashimoto R, Weimer M, et al. AHRQ Comparative Effectiveness Reviews. Noninvasive Treatments for Low Back Pain. Rockville (MD): Agency for Healthcare Research and Quality (US); 2016.

Lam M, Galvin R, Curry P. Effectiveness of acupuncture for nonspecific chronic low back pain: a systematic review and meta-analysis. Spine (Phila Pa 1976). 2013 Nov 15;38(24):2124-38.

Wellington J. Noninvasive and alternative management of chronic low back pain (efficacy and outcomes). Neuromodulation. 2014 Oct;17 Suppl 2:24-30.

Liu L, Skinner M, McDonough S, Mabire L, Baxter GD. Acupuncture for low back pain: an overview of systematic reviews. Evid Based Complement AlternatMed. 2015;2015:328196.

Taylor, P., Pezzullo, L., Grant, S. J., & Bensoussan, A. (2014). Cost-effectiveness of Acupuncture for Chronic Nonspecific Low Back Pain. Pain Pract, 14(7), 599-606. doi:10.1111/papr.12116



Ji, M., Wang, X., Chen, M., Shen, Y., Zhang, X., & Yang, J. (2015). The Efficacy of Acupuncture for the Treatment of Sciatica: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med, 2015, 192808. doi:10.1155/2015/192808

Lewis, R. A., Williams, N. H., Sutton, A. J., Burton, K., Din, N. U., Matar, H. E., . . . Wilkinson, C. (2015). Comparative clinical effectiveness of management strategies for sciatica: systematic review and network meta-analyses. Spine J, 15(6), 1461-1477. doi:10.1016/j.spinee.2013.08.049

Qin, Z., Liu, X., Wu, J., Zhai, Y., & Liu, Z. (2015). Effectiveness of Acupuncture for Treating Sciatica: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med, 2015, 425108. doi:10.1155/2015/425108


Shoulder Pain

Lee, S. H., & Lim, S. M. (2016). Acupuncture for Poststroke Shoulder Pain: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med, 2016, 3549878. doi:10.1155/2016/3549878

Wang, K. F., Zhang, L. J., Lu, F., Lu, Y. H., & Yang, C. H. (2016). Can Ashi points stimulation have specific effects on shoulder pain? A systematic review of randomized controlled trials. Chin J Integr Med, 22(6), 467-472. doi:10.1007/s11655-015-2107-4

Headache (Tension Type)

Linde K, Allais G, Brinkhaus B, Fei Y, Mehring M, Shin BC, et al. Acupuncture for the prevention of tension-type headache. Cochrane Database Syst Rev. 2016;4:Cd007587

Coeytaux RR, Befus D. Role of Acupuncture in the Treatment or Prevention of Migraine, Tension-Type Headache, or Chronic Headache Disorders. Headache. 2016 Jul;56(7):1238-40.



Linde K, Allais G, Brinkhaus B, Fei Y, Mehring M, Vertosick EA, et al. Acupuncture for the prevention of episodic migraine. Cochrane Database Syst Rev. 2016(6):Cd001218

Yang Y, Que Q, Ye X, Zheng G. Verum versus sham manual acupuncture for migraine: a systematic review of randomised controlled trials. Acupunct Med. 2016 Apr;34(2):76-83.


Neck Pain

Trinh K, Graham N, Irnich D, Cameron ID, Forget M. Acupuncture for neck disorders. Cochrane Database Syst Rev. 2016(5):Cd004870.

MacPherson, H., Tilbrook, H., Richmond, S., Woodman, J., Ballard, K., Atkin, K., . . . Watt, I. (2015). Alexander Technique Lessons or Acupuncture Sessions for Persons With Chronic Neck Pain: A Randomized Trial. Ann Intern Med, 163(9), 653-662. doi:10.7326/m15-0667


Post-operative pain

Wu MS, Chen KH, Chen IF, Huang SK, Tzeng PC, Yeh ML, et al. The Efficacy of Acupuncture in Post-Operative Pain Management: A Systematic Review and Meta-Analysis. PLOS ONE. 2016;11(3):e0150367.

Barlow T, Downham C, Barlow D. The effect of complementary therapies on post-operative pain control in ambulatory knee surgery: a systematic review. Complement Ther Med. 2013 Oct;21(5):529-34

Fransen M, Nairn L, Bridgett L, Crosbie J, March L, Parker Mbbs D, et al. Post-acute rehabilitation after total knee replacement: A multicentre randomized clinical trial comparing long-term outcomes. Arthritis Care Res (Hoboken). 2016 Nov 21.


Elbow Pain

Gadau, M., Yeung, W. F., Liu, H., Zaslawski, C., Tan, Y. S., Wang, F. C., . . . Zhang, S. P. (2014). Acupuncture and moxibustion for lateral elbow pain: a systematic review of randomized controlled trials. BMC Complement Altern Med, 14, 136. doi:10.1186/1472-6882-14-136


Carpal Tunnel Syndrome

Hadianfard, M., Bazrafshan, E., Momeninejad, H., & Jahani, N. (2015). Efficacies of Acupuncture and Anti-inflammatory Treatment for Carpal Tunnel Syndrome. J Acupunct Meridian Stud, 8(5), 229-235. doi:10.1016/j.jams.2014.11.005


Knee Osteoarthritis

Corbett MS, Rice SJ, Madurasinghe V, Slack R, FayterDA, Harden M, et al. Acupuncture and other physical treatments for the relief of pain due to osteoarthritis of the knee: network meta-analysis. Osteoarthritis Cartilage. 2013 Sep;21(9):1290-8.

Manyanga T, Froese M, Zarychanski R, Abou-Setta A, Friesen C, Tennenhouse M, et al. Pain management with acupuncture in osteoarthritis: a systematic review and meta-analysis. BMC Complement Altern Med. 2014;14:312.


Allergic Rhinitis (Hayfever)

Choi, S. M., Park, J. E., Li, S. S., Jung, H., Zi, M., Kim, T. H., . . . Baoyan, L. (2013). A multicenter, randomized, controlled trial testing the effects of acupuncture on allergic rhinitis. Allergy, 68(3), 365-374.

Xue, C. C., Zhang, A. L., Zhang, C. S., DaCosta, C., Story, D. F., & Thien, F. C. (2015). Acupuncture for seasonal allergic rhinitis: a randomized controlled trial. Ann Allergy Asthma Immunol, 115(4), 317-324.e311. doi:10.1016/j.anai.2015.05.017

McDonald JL, Smith PK, Smith CA, Changli Xue C, Golianu B, Cripps AW. Effect of acupuncture on house dust mite specific IgE, substance P, and symptoms in persistent allergic rhinitis. Ann Allergy Asthma Immunol. 2016 Jun;116(6):497-505.

Taw MB, Reddy WD, Omole FS, Seidman MD. Acupuncture and allergic rhinitis. Curr OpinOtolaryngol Head Neck Surg. 2015 Jun;23(3):216-20.

Feng, SY; Han, MM; Fan, YP; Yang, GW; Liao, ZP; Liao, W; Li, HB Acupuncture for the treatment of allergic rhinitis: A systematic review and meta-analysisAmerican Journal of Rhinology & Allergy, Volume 29, Number 1, January/February 2015, pp. 57-62(6)


Chemotherapy induced nausea

McKeon C, Smith, C.A., Hardy, J. & Chang, E. Acupunctrue and acupressure for chemotherapy-induced nausea and vomiting : a systematic review. Australian Journal of Acupuncture and Chinese Medicine. 2013;8(1):2-17.

Garcia MK, McQuade J, Lee R, Haddad R, Spano M, Cohen L. Acupuncture for symptom management in cancer care: an update. Curr Oncol Rep. 2014 Dec;16(12):418.

Molassiotis, A., Russell, W., Hughes, J., Breckons, M., Lloyd-Williams, M., Richardson, J., . . . Ryder, W. (2013). The effectiveness and cost-effectiveness of acupressure for the control and management of chemotherapy-related acute and delayed nausea: Assessment of Nausea in Chemotherapy Research (ANCHoR), a randomised controlled trial. Health Technol Assess, 17(26), 1-114. doi:10.3310/hta17260



Shergis, J. L., Ni, X., Jackson, M. L., Zhang, A. L., Guo, X., Li, Y., . . . Xue, C. C. (2016). A systematic review of acupuncture for sleep quality in people with insomnia. Complement Ther Med, 26, 11-20. doi:10.1016/j.ctim.2016.02.007

Dong, B., Chen, Z., Yin, X., Li, D., Ma, J., Yin, P., … Xu, S. (2017). The Efficacy of Acupuncture for Treating Depression-Related Insomnia Compared with a Control Group: A Systematic Review and Meta-Analysis. BioMed Research International, 2017, 9614810.

Choi, T. Y., Kim, J. I., Lim, H. J., & Lee, M. S. (2016). Acupuncture for Managing Cancer-Related Insomnia: A Systematic Review of Randomized Clinical Trials. Integr Cancer Ther. doi:10.1177/1534735416664172

Lee, S. H., & Lim, S. M. (2016). Acupuncture for insomnia after stroke: a systematic review and meta-analysis. BMC Complement Altern Med, 16, 228. doi:10.1186/s12906-016-1220-z

Lan, Y., Wu, X., Tan, H. J., Wu, N., Xing, J. J., Wu, F. S., . . . Liang, F. R. (2015). Auricular acupuncture with seed or pellet attachments for primary insomnia: a systematic review and meta-analysis. BMC Complement Altern Med, 15, 103. doi:10.1186/s12906-015-0606-7



Chang SC, Hsu CH, Hsu CK, Yang SS, Chang SJ. The efficacy of acupuncture in managing patients with chronic prostatitis/chronic pelvic pain syndrome: A systemic review and meta-analysis. Neurourol Urodyn. 2016 Jan 6.

Qin Z, Wu J, Zhou J, Liu Z. Systematic Review of Acupuncture for Chronic Prostatitis/Chronic Pelvic Pain Syndrome. Medicine (Baltimore). 2016 Mar;95(11):e3095.


Women’s Health


Chiu HY, Pan CH, Shyu YK, Han BC, Tsai PS. Effects of acupuncture on menopause-related symptoms and quality of life in women in natural menopause: a meta-analysis of randomized controlled trials. Menopause. 2015 Feb;22(2):234-44.

Dodin S, Blanchet C, Marc I, Ernst E, Wu T, Vaillancourt C, et al. Acupuncture for menopausal hot flushes. Cochrane Database Syst Rev. 2013(7):Cd007410.



Smith CA, Armour M, Zhu X, Li X, Lu ZY, Song J. Acupuncture for dysmenorrhoea. Cochrane Database Syst Rev. 2016;4:Cd007854.

Abaraogu, U. O., & Tabansi-Ochuogu, C. S. (2015). As Acupressure Decreases Pain, Acupuncture May Improve Some Aspects of Quality of Life for Women with Primary Dysmenorrhea: A Systematic Review with Meta-Analysis. J Acupunct Meridian Stud, 8(5), 220-228. doi:10.1016/j.jams.2015.06.010

Xu, T., Hui, L., Juan, Y. L., Min, S. G., & Hua, W. T. (2014). Effects of moxibustion or acupoint therapy for the treatment of primary dysmenorrhea: a meta-analysis. Altern Ther Health Med, 20(4), 33-42.



Functional dyspepsia

Lan L, Zeng F, Liu GJ, Ying L, Wu X, Liu M, et al. Acupuncture for functional dyspepsia. Cochrane Database Syst Rev. 2014(10):Cd008487.

Kim KN, Chung SY, Cho SH. Efficacy of acupuncture treatment for functional dyspepsia: A systematic review and meta-analysis. Complement Ther Med. 2015 Dec;23(6):759-66.


Irritable bowel Syndrome

MacPherson, H., Tilbrook, H., Agbedjro, D., Buckley, H., Hewitt, C., & Frost, C. (2016). Acupuncture for irritable bowel syndrome: 2-year follow-up of a randomised controlled trial. Acupunct Med. doi:10.1136/acupmed-2015-010854

Lu, Z. Z., Yin, X.J., Teng, W.J., Chen, Y.H., Sun. J., Zhao, J.M., Wang, A.Q.Bao C.H. & Shi, Y. (2015). Comparative effect of EA and moxibustion on the expression of SP and VIP in patients with IBS. Journal of Traditional Chinese Medicine, 35(4), 402-410.